Author

Manas Sehgal

Indian Institute of Science BangaloreORCID 0000-0002-1126-9481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Mohit Kumar JollyiD· 2 shared Abhijeet DasiD· 1 shared Ashwini SinghiD· 1 shared Isa MambetsarieviD· 1 shared Jeremy FrickeiD· 1 shared Mallika PrabhakariD· 1 shared Prakash KulkarniiD· 1 shared Ravi SalgiaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Mohit Kumar JollyORCID

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2 papers

Recent·Most cited

DNA walk of specific fused oncogenes exhibit distinct fractal geometric characteristics in nucleotide patterns

Abhijeet Das, Manas Sehgal, Ashwini Singh, Rishabh Goyal, Mallika Prabhakar, Jeremy Fricke, Isa Mambetsariev, Prakash Kulkarni, Mohit Kumar Jolly, Ravi Salgia

The paper uses fractal geometry and DNA walk analysis to identify distinct geometric features in nucleotide patterns of oncogenes and tumour-suppressor genes, highlighting their potential in cancer research.

Physica A Statistical Mechanics and its Applications · Feb 11, 2025Peer-reviewedBioinformatics

A systems-level analysis of the mutually antagonistic roles of RKIP and BACH1 in dynamics of cancer cell plasticity

Sai Shyam, Soundharya Ramu, Manas Sehgal, Mohit Kumar Jolly

The paper analyzes the antagonistic roles of RKIP and BACH1 in cancer cell plasticity using transcriptomic data and a gene regulatory network model, showing their association with EMT, metabolic reprogramming, immune evasion, and clinical outcomes.

Journal of The Royal Society Interface · Nov 1, 2023Peer-reviewedSystems Biology