Author

Ganesh Satyanarayana

Emory UniversityORCID 0000-0002-1136-1990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

Rabina KumpakhaiD· 3 shared Sayantan DattaiD· 2 shared Alyssa Chen· 1 shared Archeta RajagopalaniD· 1 shared Inara Jawed· 1 shared Jack T. Papania· 1 shared James T. HandaiD· 1 shared Jana T SellersiD· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMolecular Biology

Rabina KumpakhaORCID

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4 papers

Recent·Most cited

Cigarette smoke extract and palmitic acid exposed patient-derived iPS- RPE cells as a model for AMD

Rabina Kumpakha, Mohammad Akbar Bhat, Ganesh Satyanarayana, Nady Golestaneh, Sayantan Datta

This study examines how cigarette smoke extract and palmitic acid affect patient-derived iPSC-RPE cells, showing increased susceptibility in AMD-derived cells with altered stress responses and function.

bioRxiv · Nov 3, 2026 · PreprintCell Biology

Effect of Varying Cigarette Smoke Concentrations and Durations on the Retinal Pigment Epithelium

Alyssa Chen, Wei-Hsuan Lee, Suchana Das, Inara Jawed, Ganesh Satyanarayana, Rabina Kumpakha, Sayantan Datta

This study examines how different concentrations and durations of cigarette smoke condensate exposure affect oxidative stress, autophagy, EMT, and cell death in human and mouse RPE cells.

bioRxiv · Nov 2, 2026 · PreprintCell Biology

Dietary serine protects the retinal pigmented epithelium by blunting reactive oxygen species in dry age-related macular degeneration

Ganesh Satyanarayana, Rabina Kumpakha, Jack T. Papania, Jana T Sellers, Micah A. Chrenek, James T. Handa, Sayantan Datta

This study shows that dietary serine reduces ROS accumulation and improves retinal function in AMD by restoring mitochondrial function and GSH levels through PHGDH regulation.

bioRxiv · May 4, 2026 · PreprintMolecular Biology

Retinal Pigment Epithelium Injury in Pentosan Polysulfate Exposure: Morphologic Changes, Phagocytic Deficits, and Mitochondrial Dysfunction

Archeta Rajagopalan, Ganesh Satyanarayana, Rabina Kumpakha, Sakshi Shiromani, Jeffrey H. Boatright, Nieraj Jain, Sayantan Datta

This study investigates the effects of pentosan polysulfate on retinal pigment epithelium cells, finding mitochondrial dysfunction and impaired phagocytosis.

bioRxiv · Mar 31, 2026 · PreprintMolecular Biology