Developmental BiologybioRxivPreprint
Sex-specific multigenerational epigenetic responses to real-world chemical mixture exposure in an outbred sheep model
Oliver George Hargreaves, Wing Yee Kwong, Andrew Warry…·Kevin D. Sinclair
This study shows that low-level chemical exposure during pregnancy in sheep leads to sex-specific, heritable DNA methylation changes across generations, with some effects persisting in unexposed descendants.
DOI 10.64898/2026.04.08.717152