Membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing.
Emma L. James, Muy‐Teck Teh, Yufeng Li…·Eric Kenneth Parkinson
This study identifies ANKH/Ank as a novel regulator of senescence-derived extracellular citrate in humans and mice, showing its regulation by DNA damage, inflammation, and ageing.