Xiaotong Sun

The paper identifies context-specific genetic effects in neuronal activation using single-cell multiomics, revealing NPD risk variants and genes active during stimulation.

This study develops M-cTWAS to integrate multi-omics and multi-context QTL data with GWAS, improving the discovery of risk genes for complex traits.

MIRAGE improves rare variant association analysis by incorporating variant functional information, outperforming existing methods in simulations and autism exome-sequencing data.

This study integrates single-cell epigenomics with GWAS to identify risk variants and genes for Atrial Fibrillation, highlighting key transcription factors and pathways.