Author

Wesley Lewis

Yale UniversityORCID 0000-0002-1192-8862Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Yuval KlugeriD· 2 shared Fabio ParisiiD· 1 shared Francesco StrinoiD· 1 shared Junchen YangiD· 1 shared Laura E. NiklasoniD· 1 shared Micha Sam Brickman RaredoniD· 1 shared Naftali KaminskiiD· 1 shared Neeharika KothapalliiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Yuval KlugerORCID

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2 papers

Recent·Most cited

Locat: Joint enrichment and depletion testing identifies localized marker genes in single-cell transcriptomics

Wesley Lewis, Yariv Aizenbud, Francesco Strino, Yuval Kluger, Fabio Parisi

Locat identifies localized marker genes by testing both enrichment within and depletion outside cell populations in single-cell transcriptomics.

bioRxiv · Sep 17, 2026 · PreprintBioinformatics

Comprehensive visualization of cell-cell interactions in single-cell and spatial transcriptomics with NICHES

Micha Sam Brickman Raredon, Junchen Yang, Neeharika Kothapalli, Wesley Lewis, Naftali Kaminski, Laura E. Niklason, Yuval Kluger

NICHES visualizes cell-cell interactions at the single-cell level using ligand-receptor signaling proxies, enabling analysis of heterogeneous signaling across cell clusters and spatial contexts.

Bioinformatics · Dec 1, 2022Peer-reviewedBioinformatics