Biophysical characterization of Eag chaperones suggests the mechanism of effector transmembrane domain release
Matthew Van Schepdael, Iman Asakereh, Jake Colautti, Andrew J. Gierys, Kartik Sachar, Shehryar Ahmad, Mazdak Khajehpour, John C. C. Whitney, Gerd Prehna
This study investigates the mechanism by which Eag chaperones release effector transmembrane domains using biochemical, biophysical, and structural approaches.
Nature Communications · Jan 22, 2026Peer-reviewedBiochemistry