Author

Matthew Van Schepdael

University of ManitobaORCID 0009-0009-7802-8453Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Gerd PrehnaiD· 2 shared Kartik SachariD· 2 shared Andrew J. Gierys· 1 shared Iman AsakerehiD· 1 shared Jake ColauttiiD· 1 shared John C. C. WhitneyiD· 1 shared Karen A. Winters· 1 shared Mazdak KhajehpouriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Gerd PrehnaORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Structural BiologyPeer-reviewedFeb 11, 2026

Structure of the type VI secretion system protein VgrS from Salmonella Typhimurium

Kartik Sachar, Matthew Van Schepdael, Karen A. Winters, Gerd Prehna

The paper presents the X-ray crystal structure of Salmonella Typhimurium VgrS, revealing a unique open conformation and molecular variations that may influence T6SS effector loading mechanisms.

1 citation

bacteria (other)protein structure

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BiochemistryNature CommunicationsPeer-reviewedJan 22, 2026

Biophysical characterization of Eag chaperones suggests the mechanism of effector transmembrane domain release

Matthew Van Schepdael, Iman Asakereh, Jake Colautti…·Gerd Prehna

This study investigates the mechanism by which Eag chaperones release effector transmembrane domains using biochemical, biophysical, and structural approaches.

2 citationstop 4%

bacteria (other)structural biology

𝕏 PostBluesky