Marco De Zuani

This study shows sepsis causes long-term changes in human HSPCs, leading to immune dysregulation in survivors through altered myeloid progeny and metabolic reprogramming.

This study examines long-term immune changes post-COVID-19 and the impact of BCG vaccination and latent infections on disease severity.

This study identifies IL-26-expressing MAIT cells as protective for epithelial barrier function and shows their dysregulation in Crohn's disease.

This study integrates single-cell multi-omics data from human foetal blood to show that trisomy restructures enhancer-gene maps, leading to dysregulated erythroid differentiation and haematological abnormalities in Down's Syndrome.