Author

Sailan Wang

Jiangsu Province HospitalORCID 0000-0002-1269-0649Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Björn GuðbjörnssoniD· 1 shared Dan WuiD· 1 shared Daniel V. OliveiraiD· 1 shared Francesca Del GaudioiD· 1 shared Fulya TaylaniD· 1 shared Helena KarlströmiD· 1 shared Henrik ZetterbergiD· 1 shared Isabel Tapia‐PáeziD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperGenetics

Björn GuðbjörnssonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 6, 2023

Rare coding variants in NOX4 link high superoxide levels to psoriatic arthritis mutilans

Sailan Wang, Pernilla Nikamo, Leena Laasonen…·Isabel Tapia‐Páez

The paper identifies rare NOX4 variants in psoriatic arthritis mutilans patients that increase ROS levels, linking them to disease pathogenesis and suggesting therapeutic targets.

DOI 10.1101/2023.06.06.543425

humanwhole-exome sequencing

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NeuroscienceEMBO Molecular MedicinePeer-reviewedDec 16, 2022

NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model

Daniel V. Oliveira, Kirsten Coupland, Wenchao Shao…·Helena Karlström

This study shows active immunotherapy reduces NOTCH3 deposition in brain capillaries of CADASIL mice, with no adverse effects on behavior or vascular cells.

30 citations

mouseexperimental assay

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Molecular BiologyMolecular Therapy — Nucleic AcidsPeer-reviewedMay 29, 2018

Down-regulated Long Noncoding RNA HOXA11-AS affects trophoblast cell proliferation and migration by regulating RND3 and HOXA7 expression in preeclampsia

Yetao Xu, Dan Wu, Jie Liu…·Lizhou Sun

This study shows that downregulated HOXA11-AS in preeclampsia affects trophoblast proliferation and migration by regulating RND3 and HOXA7 through Ezh2/Lsd1 and miR-15b-5p mechanisms.

42 citationstop 4%

humanstatistical model

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