NeurosciencebioRxivPreprint
Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
Dorien A. Roosen, Natalie Landeck, Luis Bonet‐Ponce…·Mark Cookson
This study identifies Auxilin mutations as a cause of Parkinson's disease by showing they impair clathrin-mediated trafficking at the Golgi and synapse, leading to neuropathological lesions.
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