David C. Gershlick

The Golgi vesicle tether p115/USO1 can bind directly to the ER exit site organiser Sec16A

The paper shows that p115 binds directly to Sec16A, a protein that organizes ER exit sites, and this interaction affects secretion efficiency.

Shape2Fate: a morphology-aware deep learning framework for tracking endocytic and exocytic carriers at nanoscale.

Shape2Fate tracks and classifies exocytic and endocytic carriers in live cells using morphology-aware deep learning, revealing pathway-specific exo-endocytic coordination rules.

Dynamic subcellular proteomics identifies novel regulators of adipocyte insulin action

The paper identifies novel proteins that relocalize in adipocytes in response to insulin, highlighting their role in insulin signaling.

Volumetric single-molecule tracking inside subcellular structures

This paper introduces a method combining single-molecule light-field microscopy with widefield Fourier light-field microscopy to improve volumetric subcellular imaging and molecular diffusion analysis.

RABGAP1 acts as a sensor to facilitate sorting and processing of amyloid precursor protein

This study identifies RABGAP1 as a sensor that modulates APP trafficking and processing by regulating RAB activity on endosomal subdomains, with implications for Alzheimer's disease.

A short sequence targets transmembrane proteins to primary cilia

The paper identifies a short peptide sequence that efficiently targets transmembrane proteins to primary cilia across cell types and develops an image analysis pipeline for automated cilia measurement.

Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

This study identifies Auxilin mutations as a cause of Parkinson's disease by showing they impair clathrin-mediated trafficking at the Golgi and synapse, leading to neuropathological lesions.