Optical Screening Identifies Chemical Modulators of Intracellular α-synuclein Aggregation
Lily N. Rothschild, Colter Giem, Aditya Bajaj, Jessica W. Luo, Kimberly L. Carey, Jacques Deguine, Ramnik J. Xavier
The paper develops an optical screening system to identify small molecules modulating α-synuclein aggregation in cells and finds harman reduces aggregate formation.
bioRxiv · Jul 6, 2026 · PreprintCell Biology