Jacques Deguine

The paper links CMV exposure-associated Type 1 immunity to improved long-term survival in sepsis without shock, but not in septic shock.

The paper develops an optical screening system to identify small molecules modulating α-synuclein aggregation in cells and finds harman reduces aggregate formation.

This study uses single-cell RNA sequencing to analyze how sex and age affect gene expression and cellular interactions in healthy human liver cells.

The paper uses spatial transcriptomics to map cell types and their spatial organization in healthy and fibrotic human liver, identifying changes in hepatocyte populations during fibrosis.