Sen Xu

Emergence of Genetic Sex Determination in an Environmentally Sex-Determined Animal

The paper identifies a genetic variant in Daphnia pulex that suppresses recombination, leading to the emergence of a mixed-mating system with both genetic and environmental sex determination.

Detection of CRISPR-Cas-induced mutations in Daphnia

This study compares T7EI and FA methods for detecting CRISPR-induced indels in Daphnia magna, finding FA more reliable for accurate mutation detection.

CRISPR-Cas9-induced genetic mosaicism in three species of the microcrustacean Daphnia

This study evaluates genetic mosaicism in Daphnia species after CRISPR-Cas9 gene editing, finding mosaicism in 9 out of 11 targeted genes.

Efficient CRISPR genome editing and integrative genomic analyses reveal the mosaicism of Cas-induced mutations and pleiotropic effects of scarlet gene in an emerging model system

This study improves CRISPR editing in Daphnia pulex, reveals mutation mosaicism, and identifies gene expression changes linked to neurodegenerative disease genes in scarlet mutants.

Estimating seven coefficients of pairwise relatedness using population genomic data

This paper estimates seven pairwise relatedness coefficients from population genomic data and applies them to Daphnia pulex populations to identify related individuals and asexual clones.