Efficient CRISPR genome editing and integrative genomic analyses reveal the mosaicism of Cas-induced mutations and pleiotropic effects of scarlet gene in an emerging model system
Sen Xu, Swatantra Neupane, Hongjun Wang, Thinh Phu Pham, Marelize Snyman, Trung Viet Huynh, Li Wang
This study improves CRISPR editing in Daphnia pulex, reveals mutation mosaicism, and identifies gene expression changes linked to neurodegenerative disease genes in scarlet mutants.
bioRxiv · Jan 29, 2024 · PreprintGenomics