Author

Zhixiang Hu

Shanghai Medical College of Fudan UniversityORCID 0000-0002-1325-3459Unclaimed ORCID profile · follow to get notified of new preprints

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Zhixiang Hu1 paper

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Feifei Zhang· 2 shared Hongwu Yu· 2 shared Peng LiniD· 2 shared Qiaojuan Li· 2 shared Yan LiiD· 2 shared Yifan Wen· 2 shared Chengye LiuiD· 1 shared Huiyi HeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Feifei Zhang

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2 papers

Recent·Most cited

Cancer BiologyMedCommPeer-reviewedJul 30, 2026

Harnessing Tumor-Specific Transcript Diversity Uncovers a Shared Neoantigen Reservoir for Pancreatic Ductal Adenocarcinoma

Jingjing Zhao, Qiaojuan Li, Peng Lin…·Shenglin Huang

This paper introduces NeoAPP, a tool to identify tumor-specific transcript-derived neoantigens in PDAC, revealing a large neoantigen reservoir that could improve immunotherapy.

DOI 10.1002/mco2.70890

humanbulk RNA-seq

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Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewedJul 1, 2026

Decoding Neoantigen-encoding Tumor-Specific Transcripts Unveils a Shared Target Reservoir for Immunotherapy in Hepatocellular Carcinoma

Peng Lin, Yifan Wen, Jingjing Zhao…·Shenglin Huang

This paper identifies neoantigen-encoding tumor-specific transcripts (neoTSTs) in hepatocellular carcinoma, showing they are more abundant and immunogenic than mutation-derived neoantigens, and demonstrate therapeutic potential in preclinical models.

DOI 10.1136/jitc-2026-015428

humanbulk RNA-seq

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