U. Herrmann

This paper creates a gut transcriptomics atlas using MERFISH to show how microbiota influences cell types, spatial organization, and molecular responses in the murine gut.

This study introduces BCR-MERFISH to profile plasma cell clonality in situ using image-based single-cell transcriptomics, revealing microbiota-dependent changes and spatial distribution patterns in mice.

The paper shows that loss of PIKfyve contributes to spongiform degeneration in prion diseases by linking prion infection to PIKfyve destabilization and vacuolation.