Hao Zhang

This study shows that early hematopoietic fate decisions are not strongly influenced by bone marrow niche identity, as fate-shaping signals are redundantly provided across niches.

This paper introduces an RNA-aware preservation method, RIPIN, that improves spatial transcriptomics data quality by inhibiting RNase activity across human and mouse tissues.

This paper creates a gut transcriptomics atlas using MERFISH to show how microbiota influences cell types, spatial organization, and molecular responses in the murine gut.

The paper uses a conditional diffusion model to design a small molecule inhibitor of secondary nucleation in alpha-synuclein aggregation, showing it effectively inhibits fibril proliferation.

This study identifies H2BC1 and H2AZ.2 as critical components of H2AK119ub nucleosomes, essential for Polycomb gene silencing.