Depletion of senescent cells improves functional recovery after spinal cord injury
Diogo Paramos-de-Carvalho, Isaura Martins, Ana Margarida Cristóvão, Ana F. Dias, Dalila Neves-Silva, Telmo Pereira, Diana Chapela, Ana Farinho, António Jacinto, Leonor Saúde
The paper shows that removing senescent cells in mice with spinal cord injury improves functional recovery by enhancing myelin preservation, reducing inflammation, and promoting axonal growth.
Cell Reports · Jul 1, 2021Peer-reviewedNeuroscience