Brenda Gerull

This study identifies pathogenic autoantibodies against DSG2 in ACM patients that impair cardiomyocyte cohesion via GSK-3β activation.

This study shows that murine cytomegalovirus infection exacerbates inflammation in Pkp2 mutant mice but not in Ttn mutant mice, highlighting the interaction between genetic predisposition and environmental factors in cardiomyopathy.

This study shows apremilast improves cardiomyocyte cohesion and reduces arrhythmia in human and murine arrhythmogenic cardiomyopathy models.

This study develops a human iPSC-derived cardiac organoid model that includes macrophages and mimics aspects of cardiogenesis.