Systems BiologyPLoS Computational BiologyPeer-reviewed
Partitioning stable and unstable expression level variation in cell populations: a theoretical framework with application to the T cell receptor
Thiago Guzella, Vasco M. Barreto, Jorge Carneiro
The paper develops a framework to distinguish stable and unstable expression variation in cell populations and applies it to TCR expression in CD4 T cells, finding 70% stable variance in polyclonal populations and over 80% volatile variance in isogenic populations.
3 citations