Author

Laurent Combettes

Centre National de la Recherche ScientifiqueORCID 0000-0002-1376-4574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Fangrui Guo· 1 shared Geneviève DupontiD· 1 shared Guy Tran Van NhieuiD· 1 shared Linda Oussaedine· 1 shared Roberto Ornelas GuevaraiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Fangrui Guo

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1 paper

Recent·Most cited

Enteropathogenic E. coli-mediated Fast and Coordinated Ca2+ responses regulate NF-κB activation

Fangrui Guo, Roberto Ornelas Guevara, Linda Oussaedine, Geneviève Dupont, Laurent Combettes, Guy Tran Van Nhieu

This study shows EPEC induces fast, coordinated Ca2+ responses via eATP, leading to reduced NF-κB activation through dampened O-linked β-N-acetylglucosamine modification.

bioRxiv · Aug 6, 2025 · PreprintCell Biology