Guy Tran Van Nhieu

Enteropathogenic E. coli-mediated Fast and Coordinated Ca2+ responses regulate NF-κB activation

This study shows EPEC induces fast, coordinated Ca2+ responses via eATP, leading to reduced NF-κB activation through dampened O-linked β-N-acetylglucosamine modification.

A pre-loaded and assembled human Ago2-miRISC orchestrates Shigella-induced vacuolar rupture through the targeting of RhoGDIα

The paper shows that pre-loaded Ago2-miRISC targets RhoGDIα to facilitate Shigella-induced vacuolar rupture.

Ca2+ Regulation of Myosin II and Myosin VI during Rupture of the Shigella-Containing Vacuole

The paper shows that Ca2+ influx regulates actin dynamics and myosin II/VI activity to facilitate Shigella vacuole rupture.

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

This study determines the structural interactions between Streptococcus pyogenes M1 protein and human IgG using integrative structural biology, revealing conserved mechanisms to inhibit phagocytosis.

Cell adhesion promoted by a unique Shigella IpaA vinculin- and talin-binding site

This study identifies a unique Shigella IpaA VBS3 binding site that interacts with talin, promoting cell adhesion and bacterial invasion.