Author

Francesc Xavier Avilés

Universitat Autònoma de BarcelonaORCID 0000-0002-1399-6789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexander AdibekianiD· 1 shared Daniel AbeggiD· 1 shared Daniela CovaledaiD· 1 shared David VizarragaiD· 1 shared Ignacio FitaiD· 1 shared Jaume FarrésiD· 1 shared Jiyun ZhuiD· 1 shared Martín HugoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alexander AdibekianORCID

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1 paper

Recent·Most cited

A covalent irreversible inhibitor binds in two mutually exclusive conformations to the active-site cysteine residue of human aldehyde dehydrogenase 1A3

Daniela Covaleda, David Vizarraga, Tulsi Upadhyay, Jiyun Zhu, Daniel Abegg, Raquel Pequerul, Martín Hugo, Alexander Adibekian, Ignacio Fita, Xavier Parés, Francesc Xavier Avilés, Matthew S. Bogyo, Jaume Farrés

This paper identifies a covalent irreversible inhibitor, Z34, that binds to ALDH1A3 in two distinct conformations at the active-site cysteine, showing promise for anticancer drug development.

bioRxiv · Jul 15, 2026 · PreprintBiochemistry

Francesc Xavier Avilés · henhao