Temporal restriction of RNAi reveals breakdown of the segmentation clock is reversible after knock down of primary pair rule genes but not Wnt-signaling in the red flour beetle
Felix Kaufholz, Julia K. Ulrich, Muhammad Salim Hakeemi, Gregor Bucher
The paper shows that blocking RNAi of primary pair rule genes in red flour beetle allows segmentation recovery, but blocking Wnt pathway RNAi does not, revealing robust and labile feedback loops in segmentation.
bioRxiv · Oct 15, 2023 · PreprintDevelopmental Biology