Muhammad Salim Hakeemi

Temporal restriction of RNAi reveals breakdown of the segmentation clock is reversible after knock down of primary pair rule genes but not Wnt-signaling in the red flour beetle

The paper shows that blocking RNAi of primary pair rule genes in red flour beetle allows segmentation recovery, but blocking Wnt pathway RNAi does not, revealing robust and labile feedback loops in segmentation.

Large portion of essential genes is missed by screening either fly or beetle indicating unexpected diversity of insect gene function

The paper expands an RNAi screen in Tribolium castaneum to assess gene function diversity between beetles and flies, finding that 50% of functions are shared while others are specific to one species.

Fog signaling has diverse roles in epithelial morphogenesis in insects

This study shows that Fog signaling has multiple roles in epithelial morphogenesis across insects, including mesoderm internalization and gut development in Tribolium.

A large-scale systemic RNAi screen in the red flour beetle Tribolium castaneum identifies novel genes involved in insect muscle development

The paper reports a large-scale RNAi screen in Tribolium castaneum identifying novel genes involved in insect muscle development, with results showing both shared and distinct genes compared to Drosophila.