Author

Vincent Legagneux

InsermORCID 0000-0002-1417-6678Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Nathalie ThéretiD· 2 shared Anne SiegeliD· 1 shared Arnaud PoretiD· 1 shared Carito GuziołowskiiD· 1 shared Jérémy BomoiD· 1 shared Jérôme FerêtiD· 1 shared Lokmane CheboubaiD· 1 shared Matthieu BouguéoniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Nathalie ThéretORCID

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2 papers

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedJul 29, 2024

A rule-based multiscale model of hepatic stellate cell plasticity: critical role of the inactivation loop in fibrosis progression

Matthieu Bouguéon, Vincent Legagneux, Octave Hazard…·Nathalie Théret

This paper develops a rule-based model of hepatic stellate cell dynamics in fibrosis, showing the critical role of inactivation loops in fibrosis progression and identifying inactivated HSCs as markers of fibrosis.

15 citations

mousestatistical model

𝕏 PostBluesky

Systems BiologyBMC BioinformaticsPeer-reviewedJan 14, 2020

A pipeline to create predictive functional networks: application to the tumor progression of hepatocellular carcinoma

Maxime Folschette, Vincent Legagneux, Arnaud Poret…·Nathalie Théret

The paper introduces a pipeline to generate predictive functional networks using gene expression data and pathway databases, applied to hepatocellular carcinoma progression to identify regulatory biomolecules.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky