Author

Matthieu Bouguéon

Centre National de la Recherche ScientifiqueORCID 0009-0005-2340-7211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Anne SiegeliD· 1 shared Benjamin A. HalliD· 1 shared Jason P. WrayiD· 1 shared Jérémy BomoiD· 1 shared Jérôme FerêtiD· 1 shared Nathalie ThéretiD· 1 shared Octave Hazard· 1 shared Tariq EnveriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperSystems Biology

Anne SiegelORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 25, 2026

Dynamics of the B-Cell gene regulatory network in differentiation determine evolutionary trajectories of childhood leukaemogenesis

Matthieu Bouguéon, Jason P. Wray, Tariq Enver, Benjamin A. Hall

This study models B-cell differentiation and leukaemogenesis using a logical framework to show how mutation timing and order affect disease progression in BCP-ALL.

DOI 10.64898/2026.05.21.724796

humanstatistical model

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedJul 29, 2024

A rule-based multiscale model of hepatic stellate cell plasticity: critical role of the inactivation loop in fibrosis progression

Matthieu Bouguéon, Vincent Legagneux, Octave Hazard…·Nathalie Théret

This paper develops a rule-based model of hepatic stellate cell dynamics in fibrosis, showing the critical role of inactivation loops in fibrosis progression and identifying inactivated HSCs as markers of fibrosis.

15 citations

mousestatistical model

𝕏 PostBluesky