Author

Matheus Caetano Epifane-de-Assunção

Universidade Federal do ParáORCID 0000-0002-1421-5729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ândrea Ribeiro‐dos‐SantosiD· 3 shared Gilderlanio Santana de AraújoiD· 3 shared Bruno Lopes Santos‐LobatoiD· 2 shared Caio Santos SilvaiD· 2 shared Felipe Gouvêa de SouzaiD· 2 shared Gustavo Barra MatosiD· 2 shared Ana Gabrielle Bispo· 1 shared Andre Vitor de Souza FernandesiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Ândrea Ribeiro‐dos‐SantosORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 28, 2026

SlytheRINs: using graph parameters and residue interaction networks to analyze protein dynamics and structural ensembles

Laura Shimohara Bradaschia, Matheus Caetano Epifane-de-Assunção, Marília V. A. de Almeida…·Joao Paulo M S Lima

SlytheRINs compares conformational changes in proteins by analyzing residue interaction networks across multiple structures to identify dynamic shifts linked to functional impacts.

DOI 10.64898/2026.02.26.708270

humanprotein structure

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintJan 16, 2026

Novel mitochondrial variants associated with Parkinson's disease reveal a high heteroplasmy-weighted polygenic risk score in Brazilians

Gustavo Barra Matos, Matheus Caetano Epifane-de-Assunção, Marcella Vitoria Belem-Souza…·Bruno Lopes Santos‐Lobato

The paper identifies mitochondrial variants associated with Parkinson's disease in Brazilians and develops a polygenic risk score linked to increased disease risk.

DOI 10.64898/2026.01.15.26344224

humanwhole-genome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintNov 10, 2025

MOLECULAR ANALYSIS OF MITOCHONDRIAL COMPLEX I IN THE RESPONSIVENESS TO LEVODOPA IN PARKINSON'S DISEASE

Ana Gabrielle Bispo, Felipe Gouvêa de Souza, Matheus Caetano Epifane-de-Assunção…·Giovanna C. Cavalcante

This study identifies mitochondrial DNA variants associated with levodopa responsiveness in Parkinson's disease patients, highlighting specific subunit mutations and population-specific variants.

DOI 10.1101/2025.11.10.25339914

humanwhole-genome sequencing

𝕏 PostBluesky