BiochemistrybioRxivPreprint
Structures of Fab-stabilized CHIP reveal a conformational switch important in E3 ligase and chaperone functions
Aparna Unnikrishnan, Dong hee Chung, Emily J. Connelly…·Daniel R. Southworth
This study determines the structures of CHIP stabilized by Fab antibodies, revealing conformational switches that regulate its E3 ligase and chaperone functions.
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