Author

John J. Worthington

Lancaster UniversityORCID 0000-0002-1429-5669Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Chloe Barnes· 1 shared Jayde Whittingham‐DowdiD· 1 shared Lucy Helen Jackson-JonesiD· 1 shared Michael D. UrbaniakiD· 1 shared Nadin Fathallah· 1 shared Neil DawsoniD· 1 shared Rebecca ChatwiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Chloe Barnes

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintMay 21, 2026

Adaptive metabolic reprogramming of the brain tissue during late-stage Trypanosoma brucei infection maintains host learning and memory

Nadin Fathallah, Chloe Barnes, Rebecca Chatwin…·Michael D. Urbaniak

This study shows that during stage II of HAT infection, the brain reprograms its metabolism to use fatty acids and lipids instead of glucose, maintaining cognitive functions despite metabolic changes.

DOI 10.64898/2026.05.15.725345

mousebulk RNA-seq

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