NeurosciencebioRxivPreprint
Pak, a downstream gene of ecdysone signaling, determines left-right polarity in the Drosophila brain through neuronal cell chirality
DOI 10.1101/2025.07.15.664853
Author
Mikiko Inaki
The University of OsakaORCID 0000-0002-1448-5462Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2025 · peak 2/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship6 papers
Recent·Most cited
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Class I myosins direct circumferential F-actin flows to define cell chirality
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This study identifies Myo1D and Myo1C as drivers of chiral F-actin flows in Drosophila macrophages, contributing to cell chirality.
2 citations - Developmental BiologybioRxivPreprint
Distinctive cellular and junctional dynamics independently regulate the rotation and elongation of the internal organ
Mikiko Inaki, Takamasa Higashi, Satoru Okuda, Kenji Matsuno
The paper investigates how distinct cellular dynamics regulate simultaneous morphogenetic processes in Drosophila hindgut development.
- Developmental BiologyDevelopmentPeer-reviewed
The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis
5 citations - Developmental BiologyScientific ReportsPeer-reviewed
Live imaging of delamination in Drosophila shows that epithelial cell motility and invasiveness are independently regulated
Mikiko Inaki, Smitha Vishnu, Kenji Matsuno
The paper uses live imaging to show that cell motility and invasiveness during epithelial delamination in Drosophila are independently regulated and that motility is not required for invasiveness.
6 citations - Developmental BiologySymmetryPeer-reviewed
Statistical validation verifies that enantiomorphic states of cell chirality are determinant dictating the left- or right-handed direction of the hindgut rotation in Drosophila
Tomoki Ishibashi, Mikiko Inaki, Kenji Matsuno
The paper validates that cell chirality determines the LR direction of hindgut rotation in Drosophila through statistical analysis of genetic backgrounds.
9 citations