Jiaqiang Zhu

This study shows ASXL3 regulates cortical neuron fate through extrinsic signaling and epigenetic pathways, linking it to ASD risk.

The paper introduces SPARK, a statistical method for detecting spatially expressed genes in spatial transcriptomic data, showing it is up to ten times more powerful than existing approaches.

This study evaluates 18 dimensionality reduction methods on 30 scRNA-seq datasets to assess their accuracy, robustness, and scalability for cell clustering and lineage reconstruction.

This paper introduces PQLseq, a method for heritability estimation and differential analysis in genomic sequencing studies, showing it provides unbiased heritability estimates and better power for differential analysis.