Amani A. Gillette

This study uses optical metabolic imaging to assess how cryopreservation affects T cell metabolism and activation, finding delayed responses and identifying metabolically-fit cells linked to viability.

The paper develops an automated image analysis pipeline for wide-field optical redox imaging of patient-derived cancer organoids, achieving high accuracy and significantly faster processing than manual methods.

This study uses wide-field optical redox imaging to assess treatment response and heterogeneity in colorectal cancer organoids, showing improved sensitivity and accuracy compared to existing methods.

This study uses optical metabolic imaging to show neutrophils rapidly shift to a reduced redox state upon activation, with heterogeneous responses across cells and donors.

This paper validates Cellpose as a reliable method for segmenting single cells in autofluorescence microscopy images, showing high accuracy compared to manual segmentation.

This paper introduces a TCSPC-based flow cytometer for real-time single-cell autofluorescence lifetime analysis, demonstrating viability and sensitivity to metabolic changes in various cell types.