Author

Izabela Kowalczyk

Max Delbrück CenterORCID 0000-0002-1476-7531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Annette HammesiD· 2 shared Jessica Görne· 2 shared Alena Laier· 1 shared Anje SporbertiD· 1 shared Bettina PurfürstiD· 1 shared Chanjae LeeiD· 1 shared Elisabeth Schuster· 1 shared Franziska Witte· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

Annette HammesORCID

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2 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedJan 15, 2021

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds

Izabela Kowalczyk, Chanjae Lee, Elisabeth Schuster…·Kerstin Feistel

The paper investigates the role of Lrp2 in neural tube closure using mouse and Xenopus models, identifying its interaction with Shroom3 and Gipc1 and its role in apical constriction and planar cell polarity.

51 citations

mousezebrafish

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Developmental BiologybioRxivPreprintNov 3, 2020

Identification of novel disease relevant genetic modifiers affecting the SHH pathway in the developing brain

Nora Mecklenburg, Izabela Kowalczyk, Franziska Witte…·Annette Hammes

The paper identifies Pttg1 and Ulk4 as genetic modifiers that enhance SHH pathway resilience and are involved in primary cilia formation in the neuroepithelium.

DOI 10.1101/2020.11.03.366302

mousestatistical model

𝕏 PostBluesky