Cell BiologybioRxivPreprint
Human pluripotent stem cell-derived bronchial airway organoids provide insights into differential innate immune and long-term responses to SARS-CoV-2 infection in healthy and COPD.
Lisa Morichon, Jitendriya Swain, Nathalie Gros…·Delphine M. Muriaux
This study uses human iPSC-derived bronchial organoids to show SARS-CoV-2 causes prolonged infection, cilia destruction, and differential innate immune responses in healthy and COPD models.
DOI 10.1101/2025.06.30.662440