Pharmacology & ToxicologyScience AdvancesPeer-reviewed
Structural basis for the ligand recognition and signaling of free fatty acid receptors
Xuan Zhang, Abdul-Akim Guseinov, Laura Jenkins…·Cheng Zhang
The paper determines the structures of FFA1 and FFA4 bound to fatty acids and elucidates their activation mechanisms through cryo-EM and computational methods.
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