Revisiting the Central Dogma: the distinct roles of genome, methylation, transcription, and translation on protein expression in Arabidopsis thaliana
Ziming Zhong, Mark Bailey, Yong‐In Kim, Nazanin P. Afsharyan, Briony Parker, Louise Arathoon, Xiaowei Li, Chelsea A. Rundle, Andrew Behrens, Danny D. Nedialkova, Gancho T. Slavov, Keywan Hassani‐Pak, Kathryn Susan Lilley, Frederica L. Theodoulou, Richard Mott
This study examines the Central Dogma in Arabidopsis thaliana, showing that codon frequencies and mRNA levels are better predictors of protein expression than methylation, tRNA, or ribosome-associated transcripts.
Genome biology · Sep 29, 2025Peer-reviewedPlant Biology