Molecular BiologybioRxivPreprint
The mitoribosome-associated factor Mrx9 acts as a negative regulator of the prohibitin/m-AAA complex
Jhulia Almeida Clarck Chagas, Flavia Fontanesi, Amanda Cristina Pereira-Antonio, Mario Henrique de Barros
The paper shows that Mrx9 negatively regulates the prohibitin/m-AAA complex by impairing Yta10 and Yta12 proteolytic functions, leading to splicing defects and aberrant polypeptide accumulation.
DOI 10.64898/2026.07.28.741247