Author

Phoebe S. Parker

University of PennsylvaniaORCID 0000-0002-1512-8942Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Kara Anne BernsteiniD· 2 shared Adrian V. LeeiD· 1 shared Arjun Kumar· 1 shared Caleb M. StrattoniD· 1 shared Elena GlickiD· 1 shared Ella Roberts· 1 shared Gayatri Ganesan· 1 shared Jacob Otto KitzmaniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Kara Anne BernsteinORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 11, 2026

High-throughput mapping of 6,888 RAD51D variants identifies distinct biochemical functions needed for homologous recombination and olaparib response

Kristie E. Darrah, Shelby L. Hemker, Yashpal Rawal…·Kara Anne Bernstein

This paper maps 6,888 RAD51D variants to identify biochemical functions critical for homologous recombination and olaparib response, revealing key regions and mechanisms of variant impact.

1 citation

humanDNA methylation

𝕏 PostBluesky

GeneticsPLoS GeneticsPeer-reviewedSep 20, 2022

Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer.

Thong Luong, Zheqi Li, Nolan Priedigkeit…·Kara Anne Bernstein

This study shows that Hrq1/RECQL4 regulates DNA intrastrand crosslink repair and its misregulation contributes to genomic instability in cancer.

10 citations

yeaststatistical model

𝕏 PostBluesky