Author

Caleb M. Stratton

The University of Texas at San Antonio Health Science CenterORCID 0000-0001-7955-795XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christopher Davies· 2 shared Sandeepchowdary BalaiD· 2 shared Shaun K. OlseniD· 2 shared Allison L. Zulli· 1 shared Ann E. JerseiD· 1 shared Anna A. TumanovaiD· 1 shared Annie StevensoniD· 1 shared Anthony S. Drager· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Christopher Davies

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 10, 2026

Energetic coupling of an active site residue in penicillin-binding protein 2 from Neisseria gonorrhoeae with a resistance-associated conformational switch in the β3-β4 loop

Caleb M. Stratton, Sandeepchowdary Bala, Marissa M. Bivins…·Christopher Davies

This study investigates how Tyr422 in PBP2 couples ligand recognition to conformational changes in the β3-β4 loop, revealing energetic coupling mechanisms underlying ceftriaxone resistance in Neisseria gonorrhoeae.

DOI 10.64898/2026.08.07.743578

non-human primateprotein structure

𝕏 PostBluesky

MicrobiologyNature MicrobiologyPeer-reviewedApr 8, 2026

A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae

Tsuyoshi Uehara, Allison L. Zulli, Brittany Miller…·Stephen M. Condon

This paper identifies a novel benzoxaborinine-based inhibitor (VNRX-14079) that effectively targets penA-mediated resistance in multidrug-resistant Neisseria gonorrhoeae.

2 citations

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 11, 2026

High-throughput mapping of 6,888 RAD51D variants identifies distinct biochemical functions needed for homologous recombination and olaparib response

Kristie E. Darrah, Shelby L. Hemker, Yashpal Rawal…·Kara Anne Bernstein

This paper maps 6,888 RAD51D variants to identify biochemical functions critical for homologous recombination and olaparib response, revealing key regions and mechanisms of variant impact.

1 citation

humanDNA methylation

𝕏 PostBluesky

MicrobiologybioRxivPreprintJul 28, 2025

Inhibition of coronaviral exonuclease activity by TRIM-mediated SUMOylation

Kannan Balakrishnan, Surajit Chakraborty, Cindy Chiang…·Michaela Ulrike Gack

The paper identifies TRIM32 as an antiviral protein that inhibits SARS-CoV-2 replication by SUMOylating NSP14, thereby blocking its exonuclease activity.

2 citations

humanexperimental assay

𝕏 PostBluesky