Author

James A. West

MRC Elsie Widdowson LaboratoryORCID 0000-0002-1535-7737Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Animesh AcharjeeiD· 2 shared Julian Leether GriffiniD· 2 shared Andrew J. MurrayiD· 1 shared Antonio Murgia· 1 shared Arash YavariiD· 1 shared Bernard PrendergastiD· 1 shared Christine Hinz· 1 shared Helen E. LockstoneiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSystems Biology

Animesh AcharjeeORCID

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2 papers

Recent·Most cited

The consequences of lipid remodelling of adipocyte cell membranes being functionally distinct from global lipid storage during obesity

Kedi Liu, Animesh Acharjee, Christine Hinz, Sonia Liggi, Antonio Murgia, Júlia Dénes, Melanie K. Gulston, Xinzhu Wang, Yajing Chu, James A. West, Robert Charles Glen, Lee D. Roberts, Andrew J. Murray, Julian Leether Griffin

This study investigates lipid composition changes in white adipose tissue during obesity, showing distinct effects of lipid storage versus membrane remodeling on cellular function.

Journal of Proteome Research · Jul 10, 2020Peer-reviewedSystems Biology

Metabolic Profiling of Aortic Stenosis and Hypertrophic Cardiomyopathy Identifies Mechanistic Contrasts in Substrate Utilisation

Nikhil Pal, Animesh Acharjee, Zsuzsanna Ament, Tim Dent, Arash Yavari, Masliza Mahmod, Rina Ariga, James A. West, Violetta Steeples, Mark Philip Cassar, Neil J. Howell, Helen E. Lockstone, Kate Elliott, Parisa Yavari, William Briggs, , Julian Leether Griffin

This study compares metabolic profiles in aortic stenosis and hypertrophic cardiomyopathy, identifying distinct substrate utilization patterns and PPAR- signaling differences.

bioRxiv · Oct 13, 2019 · PreprintSystems Biology