Cell types of the human retina and its organoids at single-cell resolution: developmental convergence, transcriptomic identity, and disease map
Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, Brigitte Gross Scherf, David Goldblum, Yanyan Hou, Martin Munz, Tiago Martins Rodrigues, Jacek Król, Tamás Szikra, Rachel Cuttat, Annick Waldt, Panagiotis Papasaikas, Roland Diggelmann, Claudia P. Patino-Alvarez, , Botond Roska
This study compares cell-type development and transcriptomes in human retinal organoids and adult retinas, finding convergence in transcriptomes and cell-type-specific disease gene expression.
Cell · Sep 1, 2020Peer-reviewedNeuroscience