Author

Brigitte Gross Scherf

Institute of Molecular and Clinical Ophthalmology Basel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:non-human primate· 1

Frequent Co-Authors

Botond RoskaiD· 3 shared Cameron S. CowaniD· 3 shared Ákos KusnyerikiD· 2 shared Arjun BhariokeiD· 2 shared Arnold SzabóiD· 2 shared Claudia P. Patino-Alvarez· 2 shared David GoldblumiD· 2 shared Dinko PavlinićiD· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Botond RoskaORCID

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Author profile →

3 papers

Recent·Most cited

Embryonic cortical layer 5 pyramidal neurons form an active, transient circuit motif perturbed by autism-associated mutations

Martin Munz, Arjun Bharioke, Georg Kosche, Verónica Moreno‐Juan, Alexandra C. Brignall, Tiago Martins Rodrigues, Alexandra Graff-Meyer, Talia Ulmer, Stephanie Haeuselmann, Dinko Pavlinić, Nicole Ledergerber, Brigitte Gross Scherf, Balázs József Rózsa, Jacek Król, Simone Picelli, , Botond Roska

Cell · Apr 1, 2023Peer-reviewedNeuroscience

Cell types of the human retina and its organoids at single-cell resolution: developmental convergence, transcriptomic identity, and disease map

Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, Brigitte Gross Scherf, David Goldblum, Yanyan Hou, Martin Munz, Tiago Martins Rodrigues, Jacek Król, Tamás Szikra, Rachel Cuttat, Annick Waldt, Panagiotis Papasaikas, Roland Diggelmann, Claudia P. Patino-Alvarez, , Botond Roska

This study compares cell-type development and transcriptomes in human retinal organoids and adult retinas, finding convergence in transcriptomes and cell-type-specific disease gene expression.

Cell · Sep 1, 2020Peer-reviewedNeuroscience

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates, and humans

Josephine Jüttner, Arnold Szabó, Brigitte Gross Scherf, Rei Morikawa, Santiago B. Rompani, Miguel Teixeira, Péter Hantz, Tamás Szikra, Federico Esposti, Cameron S. Cowan, Arjun Bharioke, Claudia P. Patino-Alvarez, Özkan Keles, Chiara N. Roth, Ákos Kusnyerik, , Botond Roska

The paper develops synthetic promoter AAVs for cell-type-specific gene delivery in mice, non-human primates, and humans, showing 11% of AAVs target neuronal and glial cell types in multiple species.

Nature Neuroscience · Jul 8, 2019Peer-reviewedNeuroscience