Magdalena Renner

The paper screens 2,707 compounds in human retinal organoids to identify those that protect or damage cone photoreceptors, finding CK1 and MAPK11 inhibitors as protective.

The paper introduces FLASH-Seq, a new single-cell RNA-seq method that improves sensitivity and reduces processing time compared to existing protocols.

This paper develops a multimodal approach to study human retinal organoid development, integrating spatial, transcriptomic, and chromatin accessibility data to create a virtual atlas of retinal development.

This study compares cell-type development and transcriptomes in human retinal organoids and adult retinas, finding convergence in transcriptomes and cell-type-specific disease gene expression.

This study shows that expanded CAG repeats in HTT disrupt neural progenitor expansion and differentiation in human cerebral organoids, suggesting abnormal neurodevelopment in Huntington disease.