Author

Alain Charest

Beth Israel Deaconess Medical CenterORCID 0000-0002-1548-6950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert H. KimiD· 1 shared Aleksandar Krbanjevic· 1 shared Alexander F WangiD· 1 shared Allegra A. PettiiD· 1 shared Alycia M. Charest· 1 shared Anthony Z. WangiD· 1 shared Bhuvic PateliD· 1 shared Bryan D. ChoiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Albert H. KimORCID

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2 papers

Recent·Most cited

Long-read PacBio HiFi sequencing resolves the genomic integration site and structure of the Nestin-CreERT2KEisc/J transgene

Alycia M. Charest, Alain Charest

The paper uses PacBio HiFi sequencing to determine the genomic integration site and structure of the Nestin-CreERT2KEisc/J transgene, revealing deletions and enabling zygosity testing.

bioRxiv · Oct 2, 2026 · PreprintGenomics

Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions

Saad M. Khan, Anthony Z. Wang, Rupen R. Desai, Gyeong Dae Kim, Colin R. McCornack, Rui Sun, Sonika M Dahiya, Jennifer Ann Foltz, Ngima D. Sherpa, Katherine Xu, Harrison Olszewski, Markus Anzaldua-Campos, Yuhui Song, Elizabeth Seider, Natan Pirete Gadens, , Allegra A. Petti

This study uses spatial transcriptomics to map glioblastoma's spatial architecture, identifying tumor cell states and intercellular interactions along the core-edge axis.

bioRxiv · Apr 4, 2025 · PreprintCancer Biology