Chiara Maria Stella Herzog

This study identifies aging genes in human blood by integrating epigenetic and transcriptomic data, finding genes enriched for immune functions that better replicate across populations and link to aging outcomes.

The paper develops Biolearn, an open-source framework for curating and evaluating aging biomarkers across datasets, finding that harmonization and standardization improve their performance and generalizability.

This study examines the systemic effects of intermittent fasting in humans over six months, revealing changes in iron metabolism, immune markers, and microbiota, with implications for aging and health.

The paper presents a multi-modal atlas of lifestyle interventions showing that ageing-linked molecular features can be altered by lifestyle changes like intermittent fasting and smoking cessation.

This study evaluates molecular and clinical changes across multiple organ systems over smoking cessation using longitudinal multi-omic data from 1,094 samples.

The paper assesses the reliability of Infinium probes on Illumina Methylation arrays, identifies unreliable probes, and provides a method to exclude them using dynamic thresholds.

This paper evaluates a method using principal components for age and cancer prediction, finding it less accurate than CpG-based models despite improved reliability.