Rupert Kaul

This paper demonstrates that L. iners can be genetically manipulated using natural competence, enabling targeted gene disruptions to study its biology and potential as a probiotic.

The paper investigates the association between penile anaerobic bacteria and immune cell densities in foreskin tissue, finding increased CD11c+ myeloid cells and HIV-susceptible T cells in individuals with high bacterial abundance.

The paper develops three liquid media formulations to support rapid growth of Lactobacillus iners and other vaginal bacteria, enabling in vitro studies of their interactions.

This study examines the vaginal microbiome and immune markers before, during, and after metronidazole treatment for bacterial vaginosis, identifying distinct phases and highlighting the need for probiotics to maintain microbial balance.