Jacques Ravel

This study shows antibiotics alter immune profiles of bacterial extracellular vesicles from vaginal anaerobes, potentially causing inflammation and dysbiosis.

This study constructs a syntenic pangenome of Gardnerella, revealing new plasmids, taxonomic boundaries, and species-level differences in metabolic and virulence traits.

This study evaluates seven DTC gut microbiome testing services using standardized fecal material, revealing significant variability in analytical performance comparable to biological donor differences.

This study introduces a mathematical model to explore how nutritional resources shape the composition and stability of the human vaginal microbiota, showing that exclusive access to certain nutrients correlates with bacterial vaginosis dominance.

The paper characterizes the neovaginal microbiota and cytokine profiles in transfeminine individuals post-vaginoplasty, identifying bacterial clusters linked to immune responses and symptoms.

The paper examines vaginal microbiota, symptoms, and immune markers in transmasculine individuals on testosterone therapy, finding Lactobacillus dominance linked to adverse symptoms and inflammation.

This study identifies riboflavin production by vaginal lactobacilli and shows its role in modulating host immune responses and redox balance.

kSanity detects and quantifies bacterial strains in metagenomic data using k-mer matching, showing precision even at low coverage.

This paper develops a microphysiologic model of the cervical epithelium that replicates microbial, immunologic, and pathogenic features of STIs caused by Chlamydia and Neisseria.

The paper conducts a GWAS to identify genetic polymorphisms associated with vaginal microbiota diversity in French women using data from the PAPCLEAR cohort.

This study examines the vaginal microbiome and immune markers before, during, and after metronidazole treatment for bacterial vaginosis, identifying distinct phases and highlighting the need for probiotics to maintain microbial balance.

This study introduces VIRGO2, an enhanced gene catalog for the vaginal microbiome, revealing new bacterial species, mycobiome features, and gene expression patterns.

The paper introduces speciateIT, a fast and accurate tool for taxonomic classification of 16S rRNA gene sequences, and vSpeciateDB, a specialized reference database for vaginal microbiota.

This paper develops a stochastic model to analyze vaginal microbiome dynamics, showing how species interactions and environmental fluctuations influence microbial stability and persistence.

The paper develops metagenomic community state types (mgCSTs) to describe vaginal microbiomes by integrating composition and function, identifying associations with health outcomes and functional capabilities.

This study identifies vaginal metabolites associated with spontaneous preterm birth and shows they can predict risk with high accuracy using machine learning.

The paper shows that colonization with nonoptimal human cervicovaginal microbiota in mice leads to developmental issues and increased neonatal mortality.

The paper introduces VIRGO, a gene catalog for the vaginal microbiome, revealing high intraspecies diversity in vaginal communities.

This study characterizes the microbial community in halite endoliths, identifying a dominant archaeon with a 'salt-in' osmotic strategy and diverse viral genomes.

This study compares endolithic microbial communities in calcite and ignimbrite substrates, revealing differences in taxonomic diversity and functional adaptations to extreme aridity.